Zebra Technologies

Zebra ZD421 Healthcare Thermal Transfer Ribbon Cartridge Printer; 203 dpi, USB, USB Host, Modular Connectivity Slot, Wi-Fi, Bluetooth

Usually Ships Same Business Day
Print Technology:
Thermal Transfer
Printer Type:
Max. Print Width:
4.09 in
Print Resolution:
203 dpi
Max. Print Speed:
6 in. per second
Modular Connectivity Slot
Ribbon Cartridge
Printer Type:
MSRP: $1,211.65
Your Price: $775.46
— You save $436.19


Zebra ZD421 Healthcare Thermal Transfer Cartridge Printer - ZD421c-HC, Healthcare; Thermal Transfer Cartridge Printer ZD421c, 203 dpi, USB, USB Host, Modular Connectivity Slot, 802.11ac, BT4, USA/Canada, US Cord, Swiss Font, EZPL

Introducing the Zebra ZD421 Ribbon Cartridge Desktop Printer Thermal Transfer Cartridge Printer, designed to meet your printing needs with unparalleled efficiency and reliability.The ZD421-HC Ribon Cartridge Printer uses a catridge for instant ribbon changes that are easy with fool-proof, one-way, first-time and every-time instant loading, and a smart chip in the ribbon alerts when ribbon needs replacing.

The Zebra ZD421-HC advanced desktop printer is built specifically for healthcare enviroments. It is constructed with disinfectant-ready white plastics, UV-resistant housing with sealed button interface, and an IEC 60601-1 compliant power supply.

Features and Benefits

  • Healthcare-Ready Construction: The ZD421-HC features disinfectant-ready plastics and a sealed button interface, making it easy to clean and disinfect, helping to prevent the spread of germs and maintain a hygienic environment.
  • High-Quality Printing: Delivers crisp and clear prints with a 203 dpi resolution for labels, barcodes, and more, ensuring every detail is readable, which is essential for patient safety and accuracy.
  • Thermal Transfer Technology: Utilizes advanced thermal transfer technology, providing durable and long-lasting prints suitable for various applications.
  • Easy-to-Use Ribbon Cartridge: Simplifies the replacement process, allowing for quick and hassle-free cartridge changes, minimizing downtime and optimizing productivity.
  • Compact Desktop Design: Space-saving design makes it ideal for desktop use, fitting seamlessly into any workspace without sacrificing performance.
  • Versatile Connectivity Options: Offers flexible connectivity options including USB, Wi-Fi, Bluetooth and a Modular Connectivity Slot (for additional connection options) enabling seamless integration with your existing systems for enhanced workflow efficiency.
  • Intuitive Control Panel: User-friendly interface with five LED icons to monitor printer status, and its three-button user interface gives it added functionality and control allows for easy operation and navigation, ensuring smooth printing experiences for users of all levels. 
  • Reliable Performance: Built with Zebra's renowned quality and durability, providing consistent and reliable performance, even in demanding environments.
  • Wide Range of Applications: Perfect for a variety of applications including retail, healthcare, manufacturing, and logistics, making it a versatile solution for diverse business needs.
  • Zebra's Print DNA Software makes it easy set up, install and get your printer running quickly. PrintSecure protects printers from cyberattacks.
  • Increased printer flexibility:  Options and accessories (ordered separately) include 300 dpi, desktop battery, carrying case, peeler, cutter, keyboard display unit, mounting plate, and enclosed power supply.

The modular connectivity slot is available for field-installable 10/100 Ethernet (802.3 RJ-45) with an internal print server or serial (RS-232 DB-9) interface options.

What's in the Box:

  • Zebra ZD421-HC Thermal Transfer Printer - ZD4AH42-C01W01EZ
  • Printer, empty ribbon take-up cores (1 in. and 0.5 in.)
  • 2 - 300 m ribbon core adapters for non-Zebra ribbons
  • AC power supply and Power cord(s)
  • USB cable
  • Quick start guide
  • Regulatory guide and Saftey Guide
  • Not Included: Print Media (labels) and Thermal Transfer Ribbon  

Replaces the legacy Zebra GK Series and ZD420 Series, bringing more functionality and capability. It is powered by new innovative architecture that performs more operations simultaneously and is ready for tomorrow.

Looking for a different version of Zebra's ZD421 Barcode Label Printer?  See All Zebra ZD421 Healthcare Label Printers

Download the Zebra ZD421 Healthcare Printer Specifications Sheet  

*BTLE5 is intended for use with the Zebra printer setup mobile app only

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Manufacturer: Zebra Technologies
Model: ZD421
Part Number: ZD4AH42-C01W01EZ
Print Technology: Thermal Transfer Cartridge Printer
Printer Type Desktop - Healthcare
User Interface: 5 status icons, 3 button user interface
Connectivity: USB 2.0, USB Host, Wi-Fi (802.11ac), Bluetooth, Modular Connectivity Slot
Memory: 512 MB Flash; 256MB SDRAM
64 MB user available non-volatile memory
8 MB user available SDRAM
Maximum Print Width:  4.09 inches
Print Resolution: 203 dpi
Max. Print Speed: 6 in. per second
Media Width: 0.585 in./15 mm to 4.65 in./118 mm
Media Core Outer Diameter:  5 in.
Media Width: Thermal Transfer Cartridge: 0.585 in./15 mm to 4.65 in./118 mm
Ribbon Standard Length: Cartridge: 243 ft.
Ribbon Width: Cartridge: 4.3 in./109.2 mm
Dimensions: 10.0 in. L x 8.0 in. W x 7.0 H
Weight: 5.0 lbs.
Features: Real Time Clock, Dual-Wall Construction, Modular Connectivity Slot
Warranty: Two Year Warranty from Zebra Technologies

Learn more by downloading the Zebra ZD421 Healthcare Printer Specifications Sheet  

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